Newest Comments

  • Apply
    From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 4:21pm

    #
    Mysterymet

    Mysterymet

    Status: Bronze Member

    Joined: May 23 2020

    Posts: 89

    1+

    The whole point of science

    The whole point of science is adjusting your theories as more data becomes available. If you expect a scientist to maintain an original hypothesis even in the face of evidence to the contrary, you don’t understand scientists. Theories evolve. The scientific method works.

    Login or Register to post comments

  • From: EARLY BIRD Discount Expires Tomorrow!
  • Tue, Sep 29, 2020 - 2:13pm

    #
    dockw

    dockw

    Status: Member

    Joined: Oct 25 2010

    Posts: 4

    Covid info

    Chis,

    Have followed you for years and respect your thinking. Go to Karl Denninger’s market-ticker guy website and listen to what he has to say about T cells and immunity and treatment for the virus.
    You are an inquisitive type and will find it quite interesting. 2020- 09- 29.  Listen well my friend.
    Best to you.
    Kevin Wrynn Ed. D.  Hobe Sound Florida

     

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 2:11pm

    ontheprairie

    ontheprairie

    Status: Member

    Joined: Sep 29 2020

    Posts: 1

    ontheprairie said:

    Ronald - I have often wanted to post a question and your post finally prompted me to create an account and ask, ever since I started following PP in January.

    I have a few autoimmune diseases, many allergies as well as being born without any IGA immunoglobulin, not knowing the latter for 2/3rds of my life, but now brings past problems into clearer view. Luckily, I never needed a blood transfusion, since I would survive the first one, but not a second one without the process of having the blood "washed" first to alleviate the anaphylactic consequences.

    I have researched much and often prior to and after the introduction of the internet and feel I am knowledgeable on my particular problems, and have shared those answers with others that need help. Each person has to be their own advocate, because a Dr. that sees you for 15 minutes will never know all the idiosyncrasies of each unique individual.  I have adapted my eating and environmental toxin load through the years as more info has becomes available. Due to this, I am in my 60's, I am doing well, am in good physical health and only require one prescription (thyroid meds), since I did not have the knowledge of how to reverse that autoimmune response before the damage was done back in my early 30's. (Thankfully, I have been able to share and help younger family members to reverse their course in the past few years.)

    I have always gotten sick easily, but pushed my way through with the acquired knowledge of what helps. When covid hit, my regime already included every vitamin and supplement discussed here on PP, except to add in quercetin and more green tea to help the zinc get into the cells prophylactically.  I am fairly careful in my interactions, but have not shut myself in my house in fear - that is no life, even with my precarious situation.  I do however still have questions my research has not completely answered. With the lack of IGA, am I less likely to produce the damaging cytokine storm, since the IGA immunoglobulin mainly deals with mucus related processes, or will my other immunoglobulins take over and create the storm since I am autoimmune prone as well? Does this help or hurt my autoimmune response in this particular matter?  I know the lack of IGA is why it takes me longer to get over an infection, and is probably my biggest stumbling block in this covid thing. But you also talk about the space outside the mucus membranes. Unfortunately I have a lot of that space in my sinuses as some of my turbinates were trimmed 20 years ago and the mucus membranes scraped, which was one medical aspect that has helped me in the allergy/polyp journey. However, that also allows more particles to be breathed in - lol....... it is always something! So the next question is, does less mucus membranes create a better or worse environment for virus entry in the ACE2 receptors and subsequent penetration of the mucus layer?

    I am so thankful to have found PP and be able to glean information from so many knowledgeable individuals that take time out of their daily life to help others. Sometimes you don't realize how your contributions are exactly what someone reading needs. Thank you so much!

    Login or Register to post comments

  • From: Daily Digest 9/29 – 2020 Temps Tie For Record Hottest, Are Our Rituals Of “Prosperity” Increasingly Meaningless?
  • Tue, Sep 29, 2020 - 1:01pm

    #

    000

    Status: Bronze Member

    Joined: Dec 10 2013

    Posts: 177

    Pre-debate anger management

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 12:02pm

    #
    ronaldmignery

    ronaldmignery

    Status: Member

    Joined: Jul 03 2020

    Posts: 3

    Natural antibodies

    The near perfect exponential fit of age and mortality suggests a fundamental role of the innate immune system in covid19 infection. Within this system, there are so-called natural antibodies that are produced without the need for exposure to antigen and that fall off with aging. Once thought to be inactive, they are now known to be active in the presence of certain lectins. However, this activation seems not to enhance and rejuvenate their production, unlike the antibodies of the adaptive system. Since viruses use cell receptors for entry (covid19 uses the ACE2 receptor), natural antibodies could be selected by evolution to bind any protein that would also bind vulnerable receptors. Perhaps humans produce a natural antibody to ACE2 binding proteins that protects from any virus using that receptor. This protects youth from the virus but the protection drops off with age.
    This ACE2-like antibody might interfere with the normal function of the receptor within the tissue and so may only be activated in the lumen, the space outside the surface of mucus membranes. Here secreted dimeric immunoglobulin A would agglutinate target viruses and prevent their penetration of the mucus layer. If immunity then does not depend exclusively on blood antibodies then the percentage necessary for herd immunity could well be much lower than current thinking.

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 11:03am

    Locksmithuk

    Status: Bronze Member

    Joined: Dec 19 2011

    Posts: 124

    1+

    @ptm69 and getting it wrong

    @ptm69

    Chris used the term "intellectual integrity" very early on in his commentaries on COVID, when much learning about the virus was still occurring. His definition of that term was something like -: being open to having one's opinions or beliefs changed by new or updated knowledge. He also referred to his theories and hypotheses about the virus - by definition, these were presented as possibilities, not facts.

    If you believe that Chris' position on the virus changed because he got it wrong then perhaps you didn't understand the associated caveats.

     

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 9:53am

    #
    ezlxq1949

    ezlxq1949

    Status: Bronze Member

    Joined: Apr 29 2009

    Posts: 385

    1+

    Not all of Australia is Melbourne

    The ugly and disturbing incidents all took place in Melbourne. The rest of the country is relatively undisturbed. There is unhappiness and questioning here about over-policing and over-reacting, about health measures being enforced by blundering non-health professionals. The Premier of Victoria is earning the nickname of "Dictator Dan." Recently he sought to extend the crisis measures by one YEAR but was howled down.

    Australians by and large are placid and patient, maybe too much so. We will put up with quite a lot of inconvenience and even oppression provided we're convinced that it's in the public interest.

    In the national capital we have been only lightly affected by The Plague, and here and other parts of the country restrictions are being reduced even now.

    The good thing about the Melbourne over-reaction is that at least this segment of the population now knows what it feels like for the poor wretches we have kept in a concentration camp on Nauru and Manus for the heinous crime of attempting to come by boats rather than aeroplanes to seek safety and a refuge in Australia. And the Melbournites are learning what it's like for the Aborigines to endure chronic over-policing as part of government policy. I fear these lessons will be lost. The political classes certainly won't learn them.

    Login or Register to post comments

  • From: Charles Hugh Smith: What Would A Better System Look Like?
  • Tue, Sep 29, 2020 - 9:52am

    #

    Mark_BC

    Status: Bronze Member

    Joined: Apr 30 2010

    Posts: 401

    Mark_BC said:

    FWIW, I think that Gregory Mannarino's daily Youtube updates provide the best real-time investment advice out there in terms of understanding and accepting how corrupt and manipulated the system is, but using this to your advantage to make gains of central bank credits (dollars), however fundamentally "worthless" those are (but you can still buy a house with those "worthless" bank credits!) I think he might go off the deep end a bit with some of the commentary around Covid, but his financial analysis is spot on. He hits it home every time. Cautiously buying call options in this environment is a no-brainer IMO.

    So I think we should take the best of both worlds; prepare yourself mentally, financially and situationally for the "end" whenever that happens, but keep one foot in the mainstream to take advantage of opportunities that present themselves.

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 8:40am

    #
    Cj Sloane

    Cj Sloane

    Status: Member

    Joined: Feb 19 2020

    Posts: 32

    Cj Sloane said:

    Is it possible that the data has been adjusted to compensate for the false positives?

    Otherwise, it would seem that NY who keeps getting 700-900 new cases per day could really have almost only 300 new true cases /day

    Login or Register to post comments

  • From: Economic Impacts of Second Lockdown Will Be Severe
  • Tue, Sep 29, 2020 - 8:21am

    Cj Sloane

    Cj Sloane

    Status: Member

    Joined: Feb 19 2020

    Posts: 32

    1+

    Cj Sloane said:

    It's 1% false positive (over all) which = 30% of all of the positives being false positive.

    As I understand it if you test 100,000 you will get 1,000 false positives (1%).
    If you are getting 3,000 positive results 30% are false positives.

    Login or Register to post comments