What is the ultimate prophylactic cocktail? A thread to collect evidence

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  • Mon, May 24, 2021 - 10:14am   (Reply to #2)

    #11

    Jim H

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    Canuck – regarding H2O2 on the mucous membranes…

Have you seen any research confirming that hydrogen peroxide has some positive effect in terms of warding off this virus?  We are trying to do the evidence-based thing here and while it sounds reasonable on the surface.. I don’t personally recall seeing evidence of it being efficacious.  Best regards, Jim

PS.  Can you provide a link to the carageenan nasal spray?

  • Mon, May 24, 2021 - 11:11am   (Reply to #4)

    #12
    redeye64

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    Re: Melatonin daily?

I think that it can actually disrupt sleep.

First, I noticed that I would wake up after 4-5 hours sleep and had a hard time falling back asleep.

Second, I watched one of Andrew Huberman’s videos on sleep where he said one of the potential side affects of prolonged melatonin usage was waking up after the 3rd sleep cycle. Andrew Huberman is a Stanford neuroscientist who started recording a series of videos early this year. I think the video mentioning this one of the early ones (either on Sleep or Dreaming).

Third, when I stopped taking melatonin, things improved but I am not back to normal yet.

Sorry I do not have any other references on this. But personally I think it was a mistake to follow this bit of advice from the FLCCC because I was questioning it when I saw it. I guess I saw little harm in taking a low dose, so I went ahead. I actually researched dosages on other supplements (esp Zinc) and reduced the suggested dosages, but did not do the same for melatonin.

  • Mon, May 24, 2021 - 11:22am

    #13
    westcoastjan

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    What is the ultimate prophylactic cocktail? A thread to collect evidence

One thing I would like to see covered on this thread is what supplements to take together, at what times of day, with or without food, and what types of foods are beneficial to aiding absorption. For example I read that taking vitamin D with fatty foods is good.

Anyone care to share knowledge about this – benefits as well as potential risks? I do read a lot but also value the opinions of many here. Thanks!

  • Mon, May 24, 2021 - 11:55am

    #14
    drbrucedale

    drbrucedale

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    What is the ultimate prophylactic cocktail? A thread to collect evidence

I wrote this article a couple of months ago to summarize Chris’ and others suggestions about a prophylactic cocktail. This is the cocktail I am using myself. So far, so good. 🙂

https://drbrucedale.medium.com/while-we-wait-for-a-vaccine-cd6ad2b0b6fd

Bruce

  • Mon, May 24, 2021 - 12:45pm   (Reply to #14)

    #15
    TWalker5

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    What is the ultimate prophylactic cocktail? A thread to collect evidence

I also follow the EVMS prophylaxis protocol, minus the melatonin. As mentioned above, I fear that could have long-term negative consequences. While I haven’t seen a specific study on this for melatonin, it is common for endogenous hormone production to down regulate in the presence of consistent exogenous administration.

In light of the studies Jim has presented here I may add a silver or iota-carrageenan  nasal irrigation practice.  I need to do more research first. I also wonder if it is the substance that is most impactful or if it is simply the mechanical effect of washing out the sinuses.  I need to read the studies and see if the controls used a saline spray.

WCJan:  A, D, and E are fat soluble vitamins. No fat means no digestion/absorption.  Fortunately, most manufacturers account for this by suspending the vitamin in an oil.

  • Mon, May 24, 2021 - 12:59pm   (Reply to #4)

    #16

    Jim H

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    Melatonin daily… or not?

This is a great area of discussion.  In a retrospective analysis of medications given, Melatonin administration in hospital (generally to help sleep in patients on ventilators) was found to significantly reduce mortality.  I would therefore want to be taking it for sure if I was in the midst of fighting an infection.  Whether it belongs as part of prophylaxis is another matter and I hope that we can come to some consensus here.  I personally do not take it daily… just very infrequently at bed time.  I have not been able to perceive any great benefit to my sleep.

  • Mon, May 24, 2021 - 01:27pm

    #17

    Jim H

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    The benefits of sweat (and hot/cold cycles ala sauna- cold shower – sauna)

Dr. Seheult explores this concept here;





  • Mon, May 24, 2021 - 02:40pm   (Reply to #2)

    #18
    Canuck21

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    Carageenan nasal spray

Just google “betadine nasal spray”. If you read the package insert you will see that Betadine uses under license a molecule called Carragelose made by this company (quote from a recent press release):

“Marinomed Biotech AG (VSE:MARI), an Austrian science-based biotech company with globally marketed therapeutics derived from innovative proprietary technology platforms, announced today that Carragelose inactivates the new, rapidly spreading variants and SARS-CoV-2 wildtype with similar efficacy in vitro. The Company tested the three variants that currently mostly drive the COVID-19 pandemic, namely the so-called British or B.1.1.7, the South-African or B.1.351, and the Brazilian or P1 variant.[*] The data demonstrate that also with increasing prevalence of virus variants, the marketed OTC Carragelose-based lozenges, nasal and throat sprays will continue to effectively contribute to combatting the COVID-19 pandemic.”

https://www.marinomed.com/en/news/marinomed-biotech-ag-announces-positive-data-demonstrating-carragelose-efficacy-against-sars-cov-2-variants

Do you want more scientific articles about iota-carageenan efficacy? I have lots. I think it’s 84% efficacy if you use it 4x a day.

I will answer your Q about HP vs Sars cov2 later today. Dr David Brownstein immediately comes to mind + Dr Mercola + Dr Thomas Levy. The first and third have written books on the topic.

  • Mon, May 24, 2021 - 03:00pm   (Reply to #2)

    #19

    Jim H

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    Thanks for the info. on Carageenan nasal spray Canuck!

I just ordered some from Amazon.  I had looked for it before but didn’t realize that it was available under the Betadine brand name.  Now I will have the triad of front like mucosal treatments;

Silver nanoparticles

Carageenan

Povidone/Iodine

The povidone/Iodine stuff is pretty powerful… I don’t know that I want to use it every day.  I may use the other two daily and reserve the Povidone/Iodine for those times when I feel a sniffle or other symptom coming on.

This brings up another related topic;  Should we be thinking about a graded approach?  We could conceptually have a middle step in between long term prophylaxis, which for me will not (at least for now.. we’ll watch for the variants) include Ivermectin, and full blown, “treatment”.  I am thinking of something like this;

1)  Normal daily prophylaxis (TBD)

2) Feeling less than great, maybe sniffles;  Include now melatonin, povidone/iodine nasal flush, increased Niacin (yeah, we have not talked about this yet but we will), double Vitamin D3 dosing, double Zinc, etc.

3)  Treatment, include drugs Ivermectin, Fluvoxamine, etc.

  • Mon, May 24, 2021 - 03:53pm

    #20
    AndrewOregon

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    very hard to find chlorhexidine/benzydamine mouthwash gargles

At least in US. These are listed in I-Mask as early treatment. You can get a 2% solution chlorhexidine for sterilizing skin, but too strong.

To be clear, the Betadine nasal spray now marketed is only Carrageenan and does not contain iodine the way the skin cleaner does. So got to mix your own to cover iodine for nasal, diluted to Sandpuppy’s specs above.

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