URGENT, need list of positive HCQ studies, reports.
Has anyone compiled a list of all positive HCQ+ studies, reports, etc, that might convince a doctor to try it? We just received an email from our son about his girlfriend’s family in Hawaii. Her family is native Hawaiian and poor and it sounds like they are getting shafted on health care.
“Lola got a call from her sister earlier today, and was told her auntie has Covid. She works at Walmart and apparently got it from a co-worker. She has been self quarantining for the last week at home, but also living in that same house is Lola’s Dad and grandma! Her aunt has been staying on another floor and far away from her grandma, but apparently Lola’s Dad shares that floor with her aunt. She started getting a fever about 3 days ago, and was having a hard time breathing today, so was brought to the hospital. It’s a bit unclear what happened at that point, because Lola’s sister updated her a few hours ago and said that the aunt also has pneumonia caused by Covid, but was sent home from the hospital. They gave her steroids, but sent her home. We are very confused why she was sent back home if she has Covid and pneumonia etc!
Lola is understandably very upset and worried. Her aunt has asthma and diabetes, and her Dad also has diabetes, plus of course her grandma is in her 80s and they have all been in the same house. I’m quite scared too and don’t really know what to do.”
We don’t know if HCQ+ would help her father and grandmother, but are hooping to provide a list of links they can give the doctors. Any help would be appreciated.
i check this site occasionally, seems to have a good list:
Also see this review by members of this community:
Thanks everyone. I will forward those links to the folks in need.
Here’s my list, don’t know if it’s already listed in some of the above.
But it most likely won’t change their minds, its political and they’re covering their butts.
I think you might do better with ivermectin. You can get it over the counter for pets and on amazon. It also works
This website has a ton of studies from all around the world:
Here’s the a collection of links form a discussion I was having with friends on other social media:
The first 2 look to be good science-based articles. The second 2 are sites with collections of articles & studies- both peer & non peer reviewed.
Repositioning chloroquine as antiviral prophylaxis against COVID-19:potential and challenges
I read this one reasonable thoroughly. Excellent overview of CQ & HCQ studies to date (before covid as well as during). It includes detailed information on their histories, mechanisms of action, and why they look to be good treatments, and limitations of existing studies. Proposes a couple of different studies to be done for prophylactic use.
UC Davis review of the HCQ studies to date.
Shows 5/7 studies with positive results, but also many have bad study designs/issues. I haven’t had a chance to read this fully, but at a quick glance it looks good:
Rapid Systematic Review of Clinical Trials Utilizing Chloroquine
and Hydroxychloroquine as a Treatment for COVID-19
Collection of HCQ studies (about half peer reviewed):
I haven’t had a chance to look closely at this (including funding sources), but it shows positive & negative results, and both peer and non peer reviewed results.
Again I haven’t had a chance to look closely at this Australian site (& funding sources), but it looks to have some excellent info and clinical studies linked, as well:
It’s pretty clear that this drug is being used worldwide for treatment, when you look at articles online (general media, though possibly not via google) as well as these research articles. More on this in a couple days!
From 2005, “Chloroquine is a potent inhibitor of SARS coronavirus infection and spread” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
This is on a cellular level rather than a clinical trial with the medications, but with what we know about Covid-19 (close to SARS-Cov & using the same ACE2 pathway to enter the cells), this very much explains the mechanism of how HCQ and CQ are effective drugs against these viruses.
I have been reading up a bit, because the claims that HCQ causes heart issues are not completely unfounded, but from what I have gathered it is extremely rare, and moreso an issue with CQ than HCQ- in fact HCQ is often used instead because it has fewer side effects. In addition to reading up on that, it caught my ears when I heard that azithromycin can cause cardiac/heart issues by prolonging the qt interval. This is exactly the drug paired with HCQ in many studies! So if there is a link, it may be more likely due to that rather than HCQ. Just my theory from what I’ve read, and I have no idea why I haven’t heard anybody correlating the two. Because of this- I verified the latter comment before sharing- the rest I’m comfortable with.
What about a group of physicians & surgeons speaking out about it?
Thanks for your in depth analysis of the safety and efficacy of hydroxychloroquine (HCQ). It is interesting to note that in spite of wide spread concern that use of HCQ as a treatment for COVID-19 causes serious risk of arrhythmia a search of the literature showed the Mecuro study of 90 hospitalized patients in a Boston tertiary treatment center, the Rosenburg retrospective multicenter cohort study in New York, and a French study of 40 patients on ventilators.
The conclusion of the Boston study stated that HCQ experienced QT interval prolongation. However, this conclusion neglected to mention that the average QT gain for the administration of HCQ alone of 5.5 milliseconds was lower than the gain of the study group as a whole of 21 milliseconds (for patients with no HCQ plus those with HCQ only plus those with HCQ and azithromycin). In other words, patients without any HCQ were also experiencing increase in QT elongation over a period of time.
In the New York study the conclusion stated:
“Among patients hospitalized in metropolitan New York with COVID-19, treatment with hydroxychloroquine, azithromycin, or both, compared with neither treatment, was not significantly associated with differences in in-hospital mortality.”
Patients in the French study were in the late stage of the disease and an antiviral treatment could not be effective.
Note: Part of the misinformation that HCQ was not safe also came from the infamous Lancet study publication which had to be withdrawn due to fabrication of data.
In summary this literature search failed to find evidence of a significant hazard of qt prolongation from the administration of HCQ alone without azithromycin.