Took a dose of ivermectin last night hubby has blurry vision
So a friend of mine had lyme disease. Took ivermectin. First dose – definitely an adverse event, which he attributed to the dying bugs from Lyme. Second dose was better.
Another friend – sleepy, but just once.
Me, no reaction at all. I took it for a month, just to see what would happen. Nothing.
Although when I got my checkup yesterday, the (relatively harmless) intestinal parasites I had last year – but didn’t bother to do anything about – didn’t show up on the “stool sample” section this year.
So there’s that.
I took full dose x 5 days for sore throat and fever. No side effects at all. Symptoms relieved in two days. Didn’t get tested so don’t know that it was COVID caused.
Do not know if this is similar mechanism of action, but might have parallels. Although two different classes of drugs, the excitation of certain retinal cells could be happening.
Viagra was originally a blood pressure drug designed to work on the enzyme phosphodiesterase 5 . It coincidentally also works on the enzyme phosphodiesterase 6 which affects cells in the retina causing the Smurf vision people report.
Many Viagra users report cyanopsia, a form of chromatopsia in which a person has an abnormal color perception — in this case, unexpected blue sensations. That is, everything appears to be bluish. At a basic level, the drug works its magic by relaxing the penis muscles. It does this by inhibiting an enzyme called phosphodiesterase 5. However, Viagra inadvertently also inhibits phosphodiesterase 6, which is very similar to phosphodiesterase 5, but with far more different and unexpected effects — it overly sensitizes rod cells in the retina. These rod cells are most effective at picking up blue, so your vision becomes dominated by a blue tint.
WebMD writes that the Viagra visual effect is transitory and there’s no permanent damage.
Side Effects listed for IVM show headaches, blurred vision, and dizziness as mild and/or transitory. The issue of visual changes usually relates to treatment for onchocerciasis and the death of the worms.
Ocular side effects have included eyelid edema, anterior uveitis, blurred vision, conjunctivitis, limbitis, punctate opacity, keratitis, abnormal sensation in the eyes, and chorioretinitis/choroiditis; however, these effects are also associated with the disease onchocerciasis. Loss of vision has occurred rarely but usually resolved without corticosteroid treatment. Conjunctival hemorrhage has been reported during postmarketing experience in patients treated for onchocerciasis.[Ref]
Ivermectin doesn’t cross the blood brain barrier in vertebrates. It works on glutamate channels. Glutamate is an excitatory neurotransmitter.
Although this is not positive study, it has some good information.
COVID-19 and Ivermectin: Potential threats associated with human use
Tean Zaheer,a Kaushik Pal,b,⁎ Rao Zahid Abbas,a,⁎⁎ and María del Pilar Rodríguez Torresc
The mode of action of ivermectin is attributed to its binding affinity towards the glutamate gated ion channels, leading to hyperpolarization and paralysis of invertebrates . … ‘Ivermectin’ as an anti-parasitical has attracted great market potential, owing to the ease of use in the form of tablets, bolus, drench, pour-on, spot-on, injectables for animals and syrup, suspensions, creams and tablets for human beings…
IVM doesn’t cross the blood brain barrier in vertebrates, owing to its high specificity in targeting the glutamate-chloride ion channels of neurons . …
Ivermectin’ has been shown to very precisely target the viral capability to import innate and host proteins, bringing major conformational variations [20,21]…. IVM has been reported to specially inhibit the IMP α form and/or other enzymatic pathways, responsible for nuclear transport of viral proteins in human coronaviruses [25,26].
Strut your stuff! That was excellent.
I was exposed to Covid last Friday and found out on Monday. I had taken a small preventive dose of horse paste Ivermectin on Sunday. Took a larger dose on Monday. Was feeling “off” on Tuesday with more than usual sinus and throat irritation, slight headache, and slightly warm, so took a larger dose Tuesday (the amount recommended by FLCCC for exposure). Woke up Wednesday feeling better but with extreme light sensitivity. I was not sure if it was from Covid or Ivermectin. It abated throughout the day and is about 95% gone now. Since I feel fine I have not taken any more Ivermectin but am continuing the rest of the exposure protocol. I am being tested today (for whatever that is worth). Sunday would be my next preventive dose and I will try a small one to see if there are any side effects.
It’s unfortunate that many of us are dealing with treating ourselves on our own. since trying to educate our doctors would take too much time when we need immediate treatment and advice.
I appreciate the posts. Would like to know how everything resolves for each of you.
I know of someone who accidentally gave dogs 10 times the required dose of ivermectin due to a change in original product concentration and not adjusting the formula accordingly. The dogs had temporary blindness and loss of balance (not all dogs couldn’t see). But all resolved without issue. Only sharing this story to give some appreciation that there appears to be a large safety margin if 10 times dosing didn’t result in long term issue.
all the best
I hope that goes away quickly! I didn’t have visual issues. I tried it once and had pain in the gallbladder area (maybe pancreas?), no idea why. I had blood work done and a recent ultrasound done and everything seemed fine though. Made me nervous, though I do believe it’s likely safe for most people. I want to be able to take it if I get covid…so I hope I don’t have some unusual issue.
edited to add that I have Lyme disease, and it seems some people with Lyme have weird issues.
I love this. I would laugh at people who said the vaccine was working because it had side effects. Now I am starting to believe the it is actually true of ivermectin. Hubby’s vision is much improved today and my left eye is swollen. I am going to take another dose today to get rid of whatever virus triggered it. I have chronic fatigue and ivermectin helps that I will dance for joy.
Several years ago I had a lens implant done on my left eye to correct a developing cataract. The result was excellent. I had 20/20 vision in my left eye and near 20/20 in my right eye. It was expected that with time my right eye would also develop a cataract.
I have been taking ivermectin horse paste, weekly for about four months, with no side effects. However in retrospect, I believe there may have been some things. I had not read of any negative side effects previously so I don’t think that had an influence on me suspecting imagined side effects. Here are my thoughts:
1. Early on I noticed a slight imbalance not long after the dose which was transitory. It seems that I don’t notice the loss of balance as much now when I dose. I can’t say
if this was due to a visual effect or something else. The loss of balance was slight and short-lived.
2. I may have felt a bit tired at times after dosing, but it is probably barely worth mentioning.
3. Early on and pretty much throughout my dosing I have noticed some visual effects which are difficult to describe. It is something like an “aura” or a change in depth
4. My cataract progression on my left eye was quite slow over a period of a year or two at least. I was a little shocked to note that my right eye has rapidly deteriorated. It seems like this deterioration lines up roughly with the period of my ivermectin dosing. I cannot say for sure, but it is approximate. It seems to be the classic cataract development with blurred vision, the spiked lights and halo effect under street lights etc.
5. Some time in my fifties a mild case of seborrhea dermatitis appeared on my face which I have dealt with in various standard ways over the years. After taking my first dose of ivermectin I noticed within hours, an improvement in the condition. This may have been from the elimination of demodex mites on the face. In fact I thought I had found the cure, but though it has improved greatly, the skin flaking on the sides of the nose remain although lessened. The redness and itching has disappeared, but the flaking persists. I tried applying a small amount of ivermectin topically to see if that would work. It would improve the condition about the same as taking it orally.
6. Sometime after using ivermectin topically on my face I developed a very bloodshot right eye. It was painless and I thought perhaps I had rubbed a gnat too hard from my
eye while mowing. It took a week or two to go away. Conjunctival hemorrhage as in Hohhot’s report above?
7. I have played tennis for most of my life and the last two times I have played I have been hit in the face by the ball under my right eye while at the net. After the first shot I was sporting a beautiful black eye for a few weeks. Then it happened again. I was surprised each time because I fully expected to handle the volley. I am pretty sure I have never been hit in the face before in my lifetime of tennis, though I have been beaned a few times. My bloodshot right eye appeared before I was struck in the face. There may be something going on here with tracking the ball or depth perception, or maybe I am just getting old.
8. Aside from the normal Covid supplements, the only drug I am taking is enalapril for blood pressure.
9. I had ramped up my dosing a bit after the changes in FLCCC recommendations. I would dose maybe every five days instead of seven. After my last dose I took my dog out for a walk in bright sunlight and quickly noticed a strong visual effect. It’s not easy to describe but is like a haze or glaze combined with change in depth perception. It was strong enough to think that, “wow!, this is not normal vision”. It has subsided since. I am going to extend my dosing to at least every two weeks or possible monthly to see what happens. I have made an appointment to have the eye examined and I hope to get another lens implant if they will take me un-vaxed. I will try to report back.
One-Horse, you might want to look up Can-C cataract eye drops. I used them on my dog for several months a few years ago. I discontinued them because the dog’s cataracts were caused by progressive retinal atrophy. I used the drops in only his worse eye and much to my surprise that eye ended up being the eye with better vision. So the eye drops, which are used both by pets and humans alike, did help him even though his cataracts were from toxins being released from the deteriorating retina and not from the typical cause of cataracts.