mRNA vaccine HAS been tested in humans before?

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  • Mon, Apr 12, 2021 - 09:27am

    #1
    kshilt

    kshilt

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    mRNA vaccine HAS been tested in humans before?

Can someone help me figure this out.  It seems all the reports I have heard talk about mRNA technology being tested for years but it was always tested in animals.  The animals developed antibodies based on the vaccine but then had serious problems when exposed to live virus later and because of that human trials were never authorized.  I recently came across a few articles that talk about mRNA trials in humans back in 2015-2017.  This is a big surprise to me, and if this is the case, would we not have some long-term data from those people?

mRNA vaccines against H10N8 and H7N9 influenza viruses of pandemic potential are immunogenic and well tolerated in healthy adults in phase 1 randomized clinical trials – PubMed (nih.gov)

https://pubmed.ncbi.nlm.nih.gov/31079849

Hopefully this will get you to one of the articles I have seen.

 

  • Mon, Apr 12, 2021 - 01:34pm

    #2

    Jim H

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    This was a tiny phase I trial…

Small numbers of middle-aged, likely healthy adults.

 

  • Mon, Apr 12, 2021 - 06:29pm   (Reply to #2)

    #3
    kshilt

    kshilt

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    mRNA vaccine HAS been tested in humans before?

Even if it was a small study, it would be interesting to see what has happened to those participants and if they have any long-term injuries.

  • Wed, Apr 14, 2021 - 08:45am

    #4
    Primary Care_MD

    Primary Care_MD

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    mRNA vaccine HAS been tested in humans before?

It struck me as extremely odd that a corporation would pour R&D money into a vaccine for a disease that has virtually no risk to humans.

Most likely explanation: Moderna had to develop that ‘vaccine’ as proof-of-concept, to justify to scientists why DARPA would select them as the future mRNA ‘vaccine’ maker for the upcoming covid pandemic. Then Moderna shelved the H10N8 project and never asked the FDA to license it. (So nobody could scrutinize the data?)

“Years of work remain before Moderna would seek approval for one of its vaccines or drugs in development. The company developed the H10N8 vaccine to demonstrate the viability of its approach, rather than to bring the vaccine itself to market, Moderna Chief Executive Stephane Bancel said.

The vaccine used what Mr. Bancel described as an older technology to deliver the mRNA vaccine to the cells. The company, nevertheless, said the results provide a preliminary validation of its efforts to get cells to make disease-fighting proteins.

‘That we can make safe and effective vaccines with mRNA is now proven,’ Mr. Bancel said in an interview.”

https://www.wsj.com/articles/startup-moderna-shows-promise-in-vaccine-trial-1493308801

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