Least Worst Vaccine Option

Login or register to post comments Last Post 0 reads   9 posts
  • Fri, Aug 06, 2021 - 09:26am

    #1
    heywoodfloyd

    heywoodfloyd

    Status Member (Offline)

    Joined: Feb 05 2010

    Posts: 7

    count placeholder3

    Least Worst Vaccine Option

Like many others, I’m looking down the barrel of getting vaxxed or losing work. I’m in the US, what do people consider the least harmful at this point? Any strategy to mitigate harm, i.e. using IVM, NAC, famotidine, glutathione, etc.? I apologize if this is discussed elsewhere. Thank you.

  • Fri, Aug 06, 2021 - 09:39am

    #2
    Tealeaf10

    Tealeaf10

    Status Member (Offline)

    Joined: Jul 22 2021

    Posts: 20

    count placeholder2

    Least Worst Vaccine Option

This is such an overwhelming decision. I believe Chris felt that the adenovirus vaccine would be the better option if he was forced to choose, but I know Robert Malone just said he would avoid the adenovirus. 🤯 Not sure the exact reasoning.  I feel there are no good options, unless you can put in a religious exemption and try to hold off until novovax becomes available?  If the US even allows it!!! Impossible decision.  Using the protocol on FLCCC will probably help.

  • Fri, Aug 06, 2021 - 09:42am

    #3
    Kat43

    Kat43

    Status Gold Member (Offline)

    Joined: Feb 10 2020

    Posts: 676

    count placeholder2

    Least Worst Vaccine Option

There are supposed to be more steps to the adenovirus vaccines, meaning potentially more ways to shut them down.

  • Fri, Aug 06, 2021 - 10:23am

    #4
    wilderabbit

    wilderabbit

    Status Bronze Member (Offline)

    Joined: Dec 11 2020

    Posts: 82

    count placeholder2

    Least Worst Vaccine Option

A phase 3 clinical trial was just conducted at the large medical center in Omaha, NE. Here is what they said about Novavax:

Novavax has created a fourth COVID-19 vaccine using moth cells and tree bark. Instead of an mRNA vaccine (Pfizer, Moderna) or a viral vector vaccine (Johnson & Johnson), Novavax is a subunit protein vaccine.

“Diversity in vaccine production helps increase the number of patients vaccinated,” says Dr. Florescu. “Some might not accept mRNA vaccines, while others may be allergic to certain ingredients.”

For example, some are allergic to polyethylene glycol (PEG), an ingredient in the mRNA (Pfizer and Moderna) vaccines. There’s no polyethylene glycol (PEG) in Novavax.

How does the Novavax vaccine work?
The Novavax COVID-19 vaccine contains a protein (made using moth cells) plus an adjuvant (made from tree bark). An adjuvant is an ingredient added to boost a person’s immune response, creating higher levels of antibodies.

The Novavax vaccine uses a telltale piece of the coronavirus: the notorious spike protein. All alone, the spike protein is harmless and can’t cause COVID-19. When your immune system encounters the lonely spike protein, it produces antibodies against it. This gives you protection against future COVID-19 infection.

“Unlike mRNA vaccines, the spike protein is already premade in the Novavax vaccine. It’s a shortcut,” explains Dr. Florescu. “All the synthesis happens outside the body and we just give the end product: the spike protein.”

Like other COVID-19 vaccines, Novavax does not cause COVID-19 infection. It can’t get you sick. This vaccine doesn’t contain either live or inactivated virus.

How did they get the spike protein?
The Novavax method uses moth cells to make spike proteins:
Researchers select the desired genes that create certain SARS-CoV-2 antigens (spike protein). Researchers put the genes into a baculovirus, an insect virus. The baculovirus infects moth cells and replicates inside them. These moth cells create lots of spike proteins. Researchers extract and purify the spike proteins.

“The Novavax vaccine has no genetic material, only proteins,” says Dr. Florescu. “The vaccine technology is more traditional, and it’s very similar to a protein-based influenza vaccine.”

Influenza vaccines have also used this moth cell factory method.

What does the adjuvant (soapbark tree extract) do?
Adjuvants increase the immune response to a vaccine. In this vaccine, soapbark tree extract adjuvant makes achieving immunity possible with a smaller dose of the spike protein.

Matrix-M is the adjuvant used by Novavax. It is based on a saponin extracted from the soapbark tree (Quillaja saponaria). The soapbark extract encourages immune cells to activate, generating a more potent immune response.

Saponins are found naturally in various plant species like beans and green peas. They’re used in agriculture, animal feeds, veterinary vaccines and human food. Saponins can boost immune responses to proteins. Using the Matrix-M adjuvant, a smaller dose of spike protein achieves the desired immune response.

I don’t know when or where they will be available.

  • Fri, Aug 06, 2021 - 10:42am

    #5

    Quercus bicolor

    Status Gold Member (Offline)

    Joined: Mar 19 2008

    Posts: 987

    count placeholder2

    Easier to prevent spike damage prophylactically?

Since it’s a one time delivery of spike protein, perhaps this is true.  Also, it’s delivered outside of cells and the spike protein is on it’s own to get inside (or, more likely, I think without understanding how it may or may not get inside cells), bind with various receptors.  This seems to be the most likely mechanism of cell damage for this vaccine, so any substance that prevents receptor binding might do the trick, perhaps with the added advantage that perhaps it will not block the body’s immune response.  Of course this could be a disadvantage if natural immunity is wiped out and replaced with narrow spike protein immunity.

  • Fri, Aug 06, 2021 - 11:10am

    #6

    Jim H

    Status Bronze Member (Offline)

    Joined: Jun 08 2009

    Posts: 1593

    count placeholder2

    Mitigating harm

The J&J adenovirus-vector vax is the one that holds potential to mitigate because it must get through the membrane of your cells nucleus before beginning the process that ends with turning your ribosomes, which reside back outside the nuclear membrane, in the cytosol, into spike protein mRNA factories.  Adam has a lecture on this subject below.

My own recent research identifies another drug that can potentially work synergistically with IVM in this mission;  Mifepristone

  https://www.sciencedirect.com/science/article/abs/pii/S0166354218304595

Mifepristone, a synthetic steroid, has been evaluated for its antiviral activity.

• Treatment of mice with mifepristone interferes with the transgene expression of HAdV-based vectors.

• Mifepristone shows a dose-dependent anti-HAdV activity at low micromolar concentration.

• Mifepristone targets HAdV DNA transport to the nucleus after endosomolysis.

• Mifepristone represents a potential candidate for the development of an antiviral drug to treat HAdV infections.

  • Fri, Aug 06, 2021 - 01:52pm

    #7
    Paula Booze Casey

    Paula Booze Casey

    Status Member (Offline)

    Joined: Jul 03 2021

    Posts: 13

    count placeholder0

    Least Worst Vaccine Option

There are medical and religious exemptions which will exempt you from the vaccine.  Sidney Powell’s site has documents for a religious exemption.

  • Fri, Aug 06, 2021 - 01:55pm

    #8
    derek1ee

    derek1ee

    Status Member (Offline)

    Joined: Jul 02 2020

    Posts: 26

    count placeholder0

    Reply To: Least Worst Vaccine Option

Amongst Pfizer, ModeRNA, J&J, and Novavax, I believe many may favor Novavax if one must pick one, and I tend to agree. Here are my understanding:

1. Pfizer/ModeRNA are mRNA-based, of which the mRNA is delivered and produces the spike protein, which then triggers the immune response.

2. J&J uses viral vector to deliver DNA instead of RNA, of which also produces spike protein, rest is the same as #1.

3. Novavax is a “subunit” vaccine, of which the spike proteins are grown in the lab environment, and delivered to your body via injection.

While your body with ended up with spike protein at the end with all 3 options, there’s going to be only a fixed amount of spike protein from Novavax, since that’s what’s delivered, while Pfizer/ModeRNA/J&J delivers the genetic message for your body to produce the spike protein – is everyone’s body producing the same amount? Has this been studied?

The other concern about the Pfizer/ModeRNA is obviously that mRNA is a new tech that has never been widely used for vaccine.

The other concern for the J&J vaccine that I haven’t seen much discussion is that, whether the adenovirus used to deliver the DNA will have to be changed if booster shot is needed, since your body may recognize it the second time and kill it before it entering your cell.

However, neither option really addressed the concern of the safety of the spike protein itself though.

  • Sun, Aug 15, 2021 - 11:39am

    #9
    wilderabbit

    wilderabbit

    Status Bronze Member (Offline)

    Joined: Dec 11 2020

    Posts: 82

    count placeholder0

    Least Worst Vaccine Option

If anyone has any new information on this topic or missed it the first time around, I would be very interested in thoughts. Unfortunately, Novavax is not an option (yet).

Viewing 9 posts - 1 through 9 (of 9 total)

Login or Register to post comments