Ivermectin Prophylaxis Protocol

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  • Thu, Dec 17, 2020 - 05:18pm

    #31
    MeowCatWine

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    Ivermectin Prophylaxis Protocol

Yes hello.  So this is fun- Me, my wife, and my 1 year old are all in some level of recovery (I think) from covid after exposure from family a week and a half ago.  We think kid got it first with a low grade fever and sniffles for a few days, bounced back quick. Wife had the bad flu-like symptoms for about 5 days now. I got the sniffles, which I credit from the zinc-vD-vC-Quercetin stack I took as soon as we learned of exposure.  My test is pending.

Sniffles remain until today when I completely lost my smell and taste.  I just took the first dose of ivermectin from the DuraMectin I got a few weeks ago on Chris’ recommendation; completely freaked out at the anosmia after doing seemingly well the whole time…late stage symptom or beginning of the rough patch?  Who knows.

We’ll see what happens…and if my SIBO/fungal gut overgrowth gets cleared up in the process.

 

  • Thu, Dec 17, 2020 - 05:20pm

    #32
    Steve

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    Neighhhh, Whinny, Mihhhhhhhhhhhhhh – Ivermectin Prophylaxis Protocol

I just ingested my first round of horse paste.  Had a butterfinger candy bar chaser.

I have the urge to sleep standing up.

  • Thu, Dec 17, 2020 - 06:26pm   (Reply to #15)

    #33
    Cowgirl

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    Ivermectin Prophylaxis Protocol

J7B – If you still have it, I’m interested.  Email [email protected].  Thanks, Kathryn

  • Tue, Dec 22, 2020 - 07:23pm

    #34
    Mpup

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    Long term use of Ivermectin

Went to my doc today for my annual physical.  My labs showed acceptable Vitamin D and zinc levels though I will start taking additional Vitamin D to increase the levels a bit.  Does anyone have information as to the affects of long term use of Ivermectin?  My doc would not prescribe for prophylaxis though he would if symptomatic and tested positive.  With the current protocol by Dr. Marik of 1x weekly for prophylaxis it raises question as to the affects of long term use of ivermectin. Any thoughts on this?

Edit to add at one point the FLCCC protocol was day 1 day 3 and weekly dosage, it’s now every 2 weeks.  Odd that the EVMS protocol is day 1, day 3, and once a month?  If the once a month is effective imo that would be preferable.

don’t eat after your dose.  Instructions from my pharmacy is one hour post taking, you should take on empty stomach and stay empty for 1 hour

  • Wed, Dec 23, 2020 - 05:24am

    #36
    robie robinson

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    Ivermectin Prophylaxis Protocol

Oddly, over years of experimentation to increase effectvity on ruminants. I withheld food for approx. 12 hrs.

  • Sat, Dec 26, 2020 - 09:35am

    #38

    Ransom

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    Reply To: Ivermectin Prophylaxis Protocol

 

Ivermectin drug interactions per EVMS publication

Ivermectin has a number of potentially serious drug-drug interactions.

Please check for potential drug interaction at Ivermectin Drug Interactions – Drugs.com.

The most important drug interactions occur with cyclosporin, tacrolimus, anti-retroviral drugs and certain anti-fungal drugs.

 

Prophylaxis dosing per EVMS publication

Ivermectin for pre-exposure prophylaxis (in HCW) and for prophylaxis in high risk individuals (> 60 years with co-morbidities, morbid obesity, long term care facilities, etc). 150-200 ug/kg (or 12 mg) Day 1, Day 3 and then every 4 weeks. Dated 11-30-20, see subsequent EVMS publications for updated dosage guidance.

 

Dosing – using Durvet horse medicine products

It seems apparent there is potential for grave mistakes when using these products outside of their intended purpose. I’d hazard to guess the most likely mistake would be with over-dosing. The intention of this post is to NOT encourage their use or give advice but rather in the spirit of educational discussion so that practical methods for cross-checking dosage may be explored to the benefit and protection of smaller subjects.

 

Durvet product & IVM quantities

The tubes contain 6.08 grams of product or 6,080 milligrams. The percentage of Ivermectin in the gel is 1.87%. The quantity of Ivermectin in a full tube is 6080 x .0187 = 113.696 milligrams.

 

Dosing – using product volume

Using a digital scale (limited to 1/10th of a gram resolution) I find that filling to level the plastic end cap that comes with both the apple flavored & the Duramectin labeled Durvet 6.08g tubes results in 1 gram of product. Knowing this may prevent overdosing.

1 gram would be enough product for a weight range of 205 lbs. at the maximum dosage to 275 lbs. at the minimum dosage. In other words it’s a tiny amount & yet per the 0.2mg per kg guidance it is TOO MUCH south of 205 lbs.

1/4 of a measuring teaspoon that is filled to level is even more, equal to about 1.25 grams of the Durvet product  – I only mention this as another safety check to keep in mind.

1/8 of a level measuring teaspoon of Durvet product happens to contain (roughly & theoretically) the target 12mg prescribed amount of Ivermectin (per the EVMS prophylaxis protocol). This is the alternate flat rate dosage given for human adults without having to calculate dosage by weight.

 

Dosing – an example using weight

180 pound subject  = 81Kg

81 Kg x .2mg Ivermectin =  would take 16.2 mg undiluted Ivermectin maximum.

16.2mg / percent of Ivermectin in the product 0.0187 = 866mg (0.87gram) maximum of referenced Durvet products.

OR

Using the flat rate amount specified in the EVMS publication for adults of 12mg (undiluted) Ivermectin as a minimum dose…

12mg / .0187 = 642mg (0.64 gram) of the mentioned Durvet products.

Summary; Anything between 0.64 & 0.87 gram of the mentioned Durvet product theoretically would work for this example. 3/4 of a cap full would be about 0.75 of a gram & therefore in the range.

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Disclaimer: The information, including but not limited to, text, graphics, images, videos and other material contained in this post are for informational and educational purposes only. No material in this post is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read in this post.

  • Sat, Dec 26, 2020 - 04:04pm

    #39
    Nancki

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    Ivermectin Prophylaxis Protocol

The injectible is 1% and paste is 1.87%.  can some one show the dosing for the 1%?

  • Sat, Dec 26, 2020 - 06:11pm   (Reply to #38)

    #40
    Miles David

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    Ivermectin Prophylaxis Protocol

Thanks for posting Ransom.  I have IverCare syringes made by Farnam, also containing 1.87% ivermectin paste).

Does using the stopper on the weight markings of the syringe match the appropriate dosage you found by measuring 1/8 tsp?

  • Sun, Dec 27, 2020 - 01:18pm

    #41
    gary_lankford

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    Reply To: Ivermectin Prophylaxis Protocol

I have been using Ivermectin Injectable 1% orally as an off-label alternative to Ivermectin Sheep Drench for many years.

1% = 1gm/100ml = 10mg/ml

Dose = 200mcg/kg = 0.2mg/kg body wt.

0.2mg/kg × 1kg/2.2lb × 1ml/10mg × 100lb = ~1ml/100lb body wt

I normally guesstimate the weight of my adult ewes as 100lb, and adult rams at 150-200lb… so, a ewe gets 1ml and a ram gets 1.5 – 2ml, and lambs get guesstimated at less or just get 1ml. Sometimes, when I’ve thought wormload high, I have double dosed.

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