Ivermectin in the Equine form – is it SAFE?

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  • Wed, Oct 13, 2021 - 12:17pm

    #1
    Alan Sills

    Alan Sills

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    Ivermectin in the Equine form – is it SAFE?

I read this in a recent Mercola report: “Now, there are veterinary formulations of ivermectin. Do not use  these, as they typically contain polyethylene glycol (PEG), which is  toxic to humans.” (from 10/10/21) – Is there any way to know HOW MUCH PEG is in the horse formulations AND whether its there at all? I already contacted 1 manufacturer (duravet) – read their MSDS sheet – and asked the receptionist – all it says is “proprietary formulation” and she would not state whether it has PEG!!

I welcome all thoughts on this issue – and – even if there is PEG, is it safe in the quantities you’d take using the equine paste.

  • Wed, Oct 13, 2021 - 12:41pm

    #2
    B B

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    Ivermectin in the Equine form – is it SAFE?

I found that most equine IVMs contain glycerol formal and propylene glycol, which are considered to be “generally safe” for humans by FDA. I am not comfortable taking it prophylactically in recommended doses, but in case of emergency I will use it for sure.

  • Wed, Oct 13, 2021 - 01:09pm   (Reply to #2)

    #3
    grandefille

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    Ivermectin in the Equine form – is it SAFE?

propylene glycol is, indeed, “generally recognized as safe”.  Ethylene glycol is quite toxic to mammals.

Julie

  • Wed, Oct 13, 2021 - 01:21pm

    #4
    Mike from Jersey

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    Ivermectin in the Equine form – is it SAFE?

Here is an article raising questions about the safety of PEG.

Potential life-threatening hypersensitivity reactions to hidden molecules like macrogol may be underdiagnosed. Cases of immediate-type PEG hypersensitivity were reported with increasing frequency. The awareness regarding the allergenic potential of PEG should be raised and a proper product labelling is crucial to prevent PEG mediated hypersensitivity.

Questions about the safety of PEG

It was – in part – this article that made me start questioning the safety of the vaccines. At least one of the vaccines contains PEG.

Notwithstanding that, I own some horse paste just in case. We are living in a risk filled environment and, for myself, I don’t see any risk free decisions out there.

  • Wed, Oct 13, 2021 - 02:09pm

    #5

    Jim H

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    Ivermectin in the Equine form – is it SAFE?

Mike from NJ said,

Notwithstanding that, I own some horse paste just in case. We are living in a risk filled environment and, for myself, I don’t see any risk free decisions out there.

Life is full of risks… most we just don’t think about.. but it doesn’t mean they are not there.  Much of the insanity generated around Covid has been purposefully created by exaggerating risk way beyond the reality, as well as suppressing the means of risk reduction.

Do you worry about strep throat infections?  You know, they can potentially progress to scarlet fever and harm your heart.  Why don’t we worry incessantly about this?  We don’t because we know we can get a course of antibiotics and wipe it out via early treatment .. right?  Duh.

Similarly, those who would keep us from Covid-19 treatments will use any angle to make us fear the treatments.  OMG…. PEG!  Well, like peanuts and bee stings, some people have an overblown immune reaction to this compound.  My suggestion is to take some of your horse paste of choice as a trial and find out.  If you are particularly worried, have some Benadryl or an epi pen handy just in case.  Try a single dose at 0.2 mg/kg.  If that is fine try 0.4 mg/kg.  Remember, the molecule itself, Ivermectin, is remarkably safe.  One should be much more worried about taking acetaminophen and harming their liver.

I subscribe to the plan of having a strong, Vitamin-D3 (+ other supplements) prophylaxis, and having the horse paste on the shelf in case symptoms arise.

Again, as best I can tell the PEG concern is mostly about an allergic reaction;

    https://pubmed.ncbi.nlm.nih.gov/33011299/

J Allergy Clin Immunol Pract
. 2021 Feb;9(2):670-675. doi: 10.1016/j.jaip.2020.09.029. Epub 2020 Oct 1.

Polyethylene Glycol-Induced Systemic Allergic Reactions (Anaphylaxis)

Abstract
Polyethylene glycols (PEGs) or macrogols are hydrophilic polymers found in everyday products such as foods, cosmetics, and medications. We present 5 cases of confirmed PEG allergy, which to our knowledge is the largest case series to date. Four of the 5 cases developed anaphylaxis to medications containing PEGs, with 1 near-fatal case resulting in cardiac arrest. Skin tests were undertaken to the index medications and to PEGs of different molecular weights. Three were confirmed with positive skin prick test result to PEG, 1 confirmed with a positive intradermal test result, and 1 confirmed after positive oral challenge. Two patients developed anaphylaxis following intradermal test to PEG and 1 a systemic allergic reaction (without hypotension or respiratory distress) following PEG skin prick tests. Before diagnosis, all 5 patients were mislabeled as allergic to multiple medications and their clinical management had become increasingly challenging. An algorithm is proposed to safely investigate suspected PEG allergy, with guidance on PEG molecular weights and skin test dilutions to minimize the risk of systemic allergic reaction. Investigation carries considerable risk without knowledge and informed planning so should only be conducted in a specialist drug allergy center.

So, PEG allergy is real, but rare.  These likely come about in a way similar to latex allergy… i.e. exposure over time eventually induces an autoimmune reaction in some people.  This is a manageable risk and you can test yourself by starting with a small dose of your favorite paste… If you don’t currently have “allergies” to various meds and cosmetics, you are probably fine.

  • Wed, Oct 13, 2021 - 02:25pm

    #6
    Mike from Jersey

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    Ivermectin in the Equine form – is it SAFE?

Jim H.,

The caveat that I would place on that is this. The article I posted notes that the use of PEG is now so widespread that sensitivity is increasing in the population. Apparently, the more that people get exposed to it, the more sensitivity is showing up in the population.

Now, I know that people may claim that adverse reactions are “rare,” but is that really true? Myocarditis in response to the vaccines is alleged to be “rare,” but – considering the “narrative push” in the world right now – I have real doubts about that. The same thing could be true of studies claiming PEG sensitivity is “rare.” PEG is used widely in cosmetics, personal hygiene products, pharmaceuticals and other products. So we are talking about big profits. And I am not sure that I trust the “rare” labels when big profits are involved. It is just like with the vaccines.

Moreover, often PEG is used externally, e.g. cosmetics. But with the vaccines it is injected into the body. With the horse paste it is ingested. I think people would be well advised to be cautious.

Now, if push comes to shove, I am going to take the risk. But at least I know I am taking a risk. And it is not the risk of installing a spike protein manufacturing center in my body.

  • Wed, Oct 13, 2021 - 04:24pm   (Reply to #4)

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    PrayingForUs

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    Ivermectin in the Equine form – is it SAFE?

Pfizer contains PEG so that’s interesting. … https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vaccines-us.html#Appendix-C

  • Wed, Oct 13, 2021 - 04:33pm

    #8
    GardensAreGreat

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    Ever had a colonoscopy? PEG

Yes, the gallon of stuff you drink… the active ingredient that makes you “go” is PEG.

I personally wouldn’t worry about the bit you ingest. The volume is really small.

  • Wed, Oct 13, 2021 - 05:12pm

    #9
    skipkent

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    Ivermectin in the Equine form – is it SAFE?

I took a generous dose a few weeks ago when I felt some cold symptoms and also wanted to try it myself before offering it to any sick family members.  No adverse effects whatsoever at least not that I’m aware of :).  I ended up with a cold, no idea if it was Covid or not, fine now.

I wanted to post this because I always see a lot of opinions to these sorts of questions but rarely see a response from someone who says, “I took it myself and here’s what happened”.

  • Wed, Oct 13, 2021 - 05:21pm

    #10

    SagerXX

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    Used the horse paste…

For prophylaxis when I flew to LA to visit my mom a month ago.  One dose the day I flew, one dose the next day.  Same routine when I flew home.  No side effects whatsoever….

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