Ivermectin / HCQ / Azith or Doxycycline Dosage
Chris and Sand Puppy,
To continue our education, and to have the learning material all in one thread, Ivermectin dosage is covered above. However, since there are numerous studies out there all written for Med professionals, what is the best conventional wisdom for dosages on HCQ / Azith and/or Doxycycline? Just theoretically of course.
Did anyone ever post the recommended dosage for HCQ, Azith and doxy? I think ivermectin was well covered thanks to Chris and Sand Puppy.
I just want to make sure my study notes are complete before the pop quiz.
DISREGARD MY LAST TWO POSTS: The data I wanted is contained is this post, https://www.peakprosperity.com/forum-topic/recommended-dosage-for-hydroxychloroquine-azithromycin/
To complete this thread I’d like to add that it seems you shouldn’t take Ivermectin more than once or twice a week.
Here’s a handy dandy graph on it, and links to a very complete and informative thread from someone who’s NOT A DOCTOR, but who was theoretically interested in whats possible with Ivermectin.
I am wondering if anyone can answer a question regarding Ivermectin dosage.
I have reviewed the information stated previously that indicates the dosage is based on weight. But what if the person is over-weight? Do you base the dosage on the person’s actual current weight (even if they are carrying some extra pounds) or do you base the dosage on what the person’s ideal/normal weight is supposed to be? This is all hypothetical and I am not seeking medical advise. Thank you.
Aria, I’m not sure but I think theoretically it’s by weight.
Chris and Sand Puppy can you weigh in on the following? The CDC recommends taking Ivermectin for scabies and other diseases / parasites not more than 2 days in a row. Theoretically, the dosage for Covid is a 4 day consecutive dose.
Ivermectin’s half life is 18 hr.
Would it be best to take and adjust the dosage over 4 consecutive days, lowering the daily dosage to accommodate the build up in the body?
Or better to take a 2 day dosage, wait 5 days and take another one?
thanks so much
It looks like ivermectin is dosed by actual body weight, not “ideal body weight.” So, treat the fat cells too. 🙂
0.150 – 0.200 mg / Kg of body weight is the usual single dose. A big 220 pound (100 Kg) human, would get about 20 mg of ivermectin in a single dose.
For intestinal parasites this is given only once per month maximum.
For scabies it is dosed more often, depending on how severe the infection is.
Good web page here: Half of the dose is cleared from the body in 18 hours, 75% in 36 hours. [Edit: Oops, just noticed that Peggy linked this page and graph already.]
[T]he CDC says “Depending on [scabies] infection severity, ivermectin should be taken in three doses (approximately days 1, 2, and 8), five doses (approximately days 1, 2, 8, 9, and 15), or seven doses (approximately days 1, 2, 8, 9, 15, 22, and 29).” Notice how they are recommending taking it two days in a row (the first 2 weeks)? In that case you would have a much higher [peak] level of ivermectin in your system on the second day.
I have seen two studies of ivermectin for COVID where a single dose was given, only one time with significant benefit. Can someone else (tbp?) show other sources with multiple doses given?
The following is translated from the Portuguese using Google translate – :
The Health Secretariat of Itajaí informs that the prophylactic treatment with ivermectin is still available to the entire population in the municipality’s Centreventos. Whoever took the first dose can request the second and third by presenting a prescription. Those who have completed the cycle can still continue the treatment. On-site service is from 8 am to 6 pm, Monday to Friday. It is also possible to withdraw the medicine in health units and centers.
Altogether, more than 140 thousand people have already joined the preventive treatment to COVID-19, totaling more than two million pills delivered. The dosage of ivermectin is indicated after medical evaluation, depending on the person’s weight, and should be taken every 15 days. The intention is that the doses maintain the plasma level of the drug in the person’s body during the pandemic months.
To start the treatment, the resident must inform the personal data, such as full name, date of birth, CPF, weight, mother’s name and address. Whoever has started the medication can withdraw the other doses by presenting the prescription. The fourth and fifth doses of ivermectin are also being delivered to residents who are interested in continuing preventive treatment.
Despite the treatment, the Municipality of Itajaí still reinforces the importance of the population maintaining social isolation whenever possible and all preventive measures, such as hand hygiene, cough etiquette, not participating in agglomerations, among others.
The website is:
Thanks so much for your thoughts on this fascinating topic!
Let me give you a theoretical situation for long haulers:
If one dose of ivermectin helped but didn’t clear a covid infection, and it came back, would an extended treatment be advised?
If so, should the 4-day Covid protocol take into account ivermectin build up in the body, with the recommended dosage reduced accordingly*?
Or would the CDC’s recommended treatment for acute scabies be better: 2 days on, 5 days off, another 2 days on five days off, etc?
*Some long haulers have math brains and can do the calculations, so no problem there.
Discussion of Ivermectin’s role as a broad spectrum anti-viral.
“Ivermectin proposes many potentials effects to treat a range of diseases, with its antimicrobial, antiviral ….
Zika, dengue, yellow fever, West Nile, Hendra, Newcastle, Venezuelan equine encephalitis, chikungunya, Semliki Forest, Sindbis, Avian influenza A, Porcine Reproductive and Respiratory Syndrome, Human immunodeficiency virus type 1, and severe acute respiratory syndrome coronavirus 2.
Furthermore, there are some studies showing antiviral effects of Ivermectin against DNA viruses such as Equine herpes type 1, BK polyomavirus, pseudorabies, porcine circovirus 2, and bovine herpesvirus 1…”
It looks like the Ivermectin does not directly interfere with viral replication, but with host response to infection. This is why it is so broad spectrum.
Yet it blocks the virus getting into the cells, or? (I guess thats another way of saying what you just said.)