Drawbacks to Chronic Prophylaxis?

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  • Wed, Nov 24, 2021 - 01:13pm

    #1
    TWalker5

    TWalker5

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    Drawbacks to Chronic Prophylaxis?

I’m wondering if long term prophylaxis could have a negative impact on immunity.

I have horse paste in reserve but do not take it preventatively. I have taken 50 mg of zinc, along with 1000 mg quercetin daily for about 20 months now.  As zinc blocks viral replication, it made sense to me to use it as a prophylactic.  And in this n = 2 experiment (my wife and I) it has worked well.  But I am a bit worried that if viruses never get a foothold in my body, perhaps this could be a long term negative for our acquired immunity.  Might this potentially make us more vulnerable down the road, particularly when combined with the masking, distancing and hypersanitation present in today’s society?  Or am I just overthinking this?

  • Wed, Nov 24, 2021 - 01:55pm

    #2
    Kat43

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    Drawbacks to Chronic Prophylaxis?

In my opinion, long term supplementation with zinc must be accompanied by copper, at a ratio of 15Z:1C or 15Z:2C, approximately.  I’m taking quite a few supplements but reserving IVM for symptoms.  Maybe because I’m really not exposed to much of anything, I don’t see the need for 50 mg zinc/day.  I’m taking quite a bit less (with copper).

I do think the lockdowns/social distancing, as an example, could be eroding our immune systems, especially in children.  We need frequent exposure, just not at very high levels.  I hadn’t thought about whether long-term antiviral supplements could be a problem.

 

  • Wed, Nov 24, 2021 - 02:05pm

    #3

    Jim H

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    Great topic TWalker

I also decided some time ago to reserve IVM only in case of incipient infection or symptoms.  I do worry a bit about Zinc overload – it’s important to either take a formulation that includes some balancing Copper, or to take small amounts (I have 2 mg pills) separately.

As for limiting acquired immunity… I don’t see this as a worry.  Philosophically, what I am trying to achieve through prophylaxis is to have innate immunity equivalent to a much younger person.  High Vitamin D3 sufficiency for instance has been proven to be protective against a large swath of infectious disease, both viral and bacterial.  I am happy never to get those infections.

I think our sensibilities have been warped in many ways as a result of the Covid-19 propaganda.  We don’t need antibodies to everything.  Yes, natural immunity to Covid-19 is great if you can get it without having any lingering effects from the Covid-19 infection.. but I am getting more comfortable with my lack thereof.  In a sense, the longer I hold out with no acquired immunity, while keeping my anti-viral prophylaxis and early treatment store shelves full, the better off I will be from the standpoint of original antigenic sin ((better to have today’s (variant) infection vs yesterday’s)).

That’s my positive spin.. I am open to arguments that I myself am engaging in narrative creation : )

 

 

 

  • Wed, Nov 24, 2021 - 02:14pm

    #4
    2retired

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    Drawbacks to Chronic Prophylaxis?

There are numerous examples that being ‘too clean’ has its drawbacks and avoidance of all immune exposure/stimulants is probably not a good thing. I believe (!) that the immune system is like a muscle, it needs exercise to be strong. Prophylaxis may be a benefit with high, specific, exposure risks, but we will all be exposed to covid and its variants if we live long enough, so tempering your risks, yes, can you avoid it forever, no.

  • Wed, Nov 24, 2021 - 04:12pm

    #5

    Oliveoilguy

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    Drawbacks to Chronic Prophylaxis? Yes!

As I posted about a month ago my doctor (who prescribes IVM and HCQ) told me to not use the IVM unless I was exposed or starting to feel sick. He feels that there is not enough data on long term buildup of the drug in the human body.

Following his recommendation, I stopped IVM prophylaxis which had been 200 mcg/kg of body weight once a week.

I have continued with D3 Zinc, Quercetin and Vitamin C.

  • Wed, Nov 24, 2021 - 05:44pm

    #6
    LBL

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    Reply To: Drawbacks to Chronic Prophylaxis?

30 mg of Zinc gives you 76 Million Zinc ions/atoms per cell.

I stopped taking Zinc.  I think the Zinc we get in vegetables & fruit is enough.

What density of Zinc do we need in our cells for our immune system to do its job ?

Zinc can be slightly neurotoxic.  That’s the reason our cells are built to stop Un-escorted Zinc ions at the cell wall.

https://pubmed.ncbi.nlm.nih.gov/28889274/

https://www.google.com/search?q=Zinc+can+be+slightly+neurotoxic

= = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = = =

Zinc atomic weight 65 grams per mole
6 x 10^23

30 mg =
4.6153846153846153846153846153846e-4

.00046 moles

.00277 x 10^23
2.8 x 10^20, 28 x 10^19

# of cells in the human body
https://www.nationalgeographic.com/science/article/how-many-cells-are-in-your-body
37 Trillion = 3.7 x 10^12

==> 7.5675675675675675675675675675676
7.6 x 10^7 Zinc ions or atoms per cell.

That’s probably enough.

You could sweat & poop out 90% of the Zinc, and be left with 7.6 x 10^6, i.e. 7.6 million Zinc ions/ atoms.

I have a feeling that is enough.

To know more we would need to know how many zinc “receptors” (vulnerable locations) on a Virus molecule and what background concentration will produce a pressure (like diffusion) that gets a Zinc ion everywhere the cellular immune system needs it.

Also important to balance with Copper

  • Wed, Nov 24, 2021 - 06:26pm

    #8
    Jane B

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    Drawbacks to Chronic Prophylaxis?

I recently gave up IVM prophylaxis as natural immunity is desired. I also cut my zinc use in half as I realized my sense of smell had become dull. I also need to balance more often with kale/spinach for both copper and Vit k. Good Grief, this balancing act is challenging

  • Wed, Nov 24, 2021 - 07:15pm

    #9

    Matt Holbert

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    I saved my IVM until I got symptoms…

and then I followed the FLCCC early outpatient treatment protocol until symptoms (shortness of breath, mild chest pain, and fatigue) went away after 6 days. Whatever I had — and I have not been tested — was far better than the flu. 63 year old male with a BMI of slightly less than 30 and no comorbidities…

  • Wed, Nov 24, 2021 - 10:05pm

    #10
    TWalker5

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    Drawbacks to Chronic Prophylaxis?

Thank you all for your thoughtful replies.  I may cease, or at least reduce my zinc intake, but my consideration of this continues.  Jane summed it up well.  This balancing act is quite challenging, indeed.

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