COVID-19: The Ivermectin African Enigma

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  • Fri, Dec 25, 2020 - 05:23am

    #1
    The Finn

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    COVID-19: The Ivermectin African Enigma

Does a study with a population of 0.78 billion and control group of 0.56 billion people have any scientific significance?

COVID-19: The Ivermectin African Enigma

https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/4613/4862

Guerrero R, Bravo LE, Muñoz E, Grillo AEK,  Guerrero E. COVID-19: The Ivermectin African Enigma. Colomb Med (Cali). 2020

Maybe the explanation is that they use so much hydroxychloroquine there. WHO knows.

Off-Label Use of Chloroquine and Hydroxychloroquine for COVID-19 Treatment in Africa Against WHO Recommendation

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7505701/

Belayneh, Anteneh. “Off-Label Use of Chloroquine and Hydroxychloroquine for COVID-19 Treatment in Africa Against WHO Recommendation.” Research and reports in tropical medicine vol. 11 61-72. 17 Sep. 2020.

Happy holidays!

 

  • Sat, Dec 26, 2020 - 04:16pm

    #2
    Joegrane

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    COVID-19: The Ivermectin African Enigma

COVID-19: The Ivermectin African Enigma:

A few selected notes from the paper:

“Our study aimed to describe SARS-CoV2 infection and death rates in African countries that participated in an intensive Ivermectin mass campaign carried out to control onchocerciasis and compare them with those of countries that did not participate.”

“After controlling for different factors, including the Human Development Index,
APOC countries [providing Ivermectin] (vs. non-APOC), show 28% lower mortality …and 8% lower rate of infection …due to COVID-19”

  • Sun, Dec 27, 2020 - 12:29am

    #3
    Dhakapapa

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    COVID-19: The Ivermectin African Enigma

Another significant result with Ivermectin in Bangladesh :

 

https://www.dhakatribune.com/health/coronavirus/2020/12/26/bangladeshi-researchers-find-ivermectin-effective-as-covid-19-preventive-drug

 

I post only the graph here:

The question I remain with: they gave Ivermectin 12 mg on a monthly basis, whilst the half-time is 18 hours. Is that enough? How can that still work ?

 

  • Sun, Dec 27, 2020 - 01:03am   (Reply to #2)

    #4
    The Finn

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    COVID-19: The Ivermectin African Enigma

Thank you for the notes @Joegrane.

Your copy-paste is of course correct. Their results summary wording seems to be a bit misleading. Maybe it is a translation issue.

Raw numbers from their Table 1:

APOC cases 407 per million and deaths 7.8 per million.

Non-APOC cases 2,453 per million and deaths 62 per million.

They do some adjustments, but their raw data would imply that improvement in number of cases would be some 6 times and in mortality some 8 times.

 

 

  • Sun, Dec 27, 2020 - 02:47am   (Reply to #3)

    #5
    RandomMike

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    COVID-19: The Ivermectin African Enigma

Dhakapapa:

Perhaps the half-life of ivermectin hasn’t been thoroughly investigated. That is, if it walks like a month of immunity and talks like a month of immunity, it might be a month of immunity.

  • Sun, Dec 27, 2020 - 03:54am

    #6
    robie robinson

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    Reply To: COVID-19: The Ivermectin African Enigma

The withdrawal time for cattle is 55 days and sheep 30 days. ie. when used on ruminants, the time from administration of ivermectin to animal slaughter must exceed approximately one month.

  • Sun, Dec 27, 2020 - 05:33am   (Reply to #6)

    #7
    Dhakapapa

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    COVID-19: The Ivermectin African Enigma

Thank you for that information robie robinson.

The MATH+ protocol prescribes ivermectin on day 1, day 3 and then every four weeks. I live in a high risk area and I am at high risk for a dangerous turn of events in case the virus would have its way with me. Your explanation reassured me and I will wait to take the next dose.

And thanks RandomMike for the humour, we can use it in times like these.

 

  • Sun, Dec 27, 2020 - 07:26am

    #8
    The Finn

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    Reply To: COVID-19: The Ivermectin African Enigma

@dhakapapa and others…

Thank you for the post. I thought that all of you here follow the Ivermectin is effective for COVID-19: meta analysis.

https://ivmmeta.com/

Alam et al., European Journal of Medical and Health Sciences, Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Study has been duly added as it came out.

Sorry about that. The meta analysis is so good maybe I start a new thread on that… Let’s try to focus this thread on Africa – if anyone would have any additional information on the African situation or circumstances.

 

  • Sun, Dec 27, 2020 - 07:47am   (Reply to #6)

    #9
    Kat43

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    COVID-19: The Ivermectin African Enigma

Dr. Marik says that IVM settles in adipose tissue.  I assume that is why it might not be found for long in serum.

Yes Dr Marik explained in detail how the dosage recommendation of Ivm saturates the adipose tissue which in turn provides protection from the virus. I’d advise those interested to watch his video.

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