Azithromycin mechanism of action study

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  • Wed, Mar 25, 2020 - 04:59pm

    #1
    lyn808

    lyn808

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    Azithromycin mechanism of action study

Dear All:

Fun abstract (no free access to arti; anyone?). I’ll just leave this here:

https://www.ncbi.nlm.nih.gov/pubmed/31300721

Cliff notes (from the other half, who has an edu background in virology):

Maybe not ribosomal inhibition, but endocytosis inhibition.

All the best.

  • Wed, Mar 25, 2020 - 05:47pm

    #2
    Mots

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    Azithromycin mechanism of action study

lyn808
Thanks for referral to this note about how intranasal delivery of azithromycin inhibits corona virus infection to the mucosal layer there.

A key point: how did they deliver intranasally?  Secondly, can this be administered via nebulizer?  Any report of nebulization to deliver intranasally and also to the lungs?

  • Thu, Mar 26, 2020 - 09:07am

    #3
    lyn808

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    Azithromycin mechanism of action study

Thanks, all good questions, @Mots. As I alluded to parenthetically, I don’t have access to the full article. Was hoping one of our compatriots does, and could further illuminate.

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