Antihistamines Again: Spanish Nursing Home Study

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  • Sat, Jun 26, 2021 - 07:58am

    #1
    davefairtex

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    Antihistamines Again: Spanish Nursing Home Study

So another signal suggesting that the antihistamines really might be working.  This pair of nursing homes in Spain did extremely well compared to their neighbors.

https://twitter.com/Covid19Crusher/status/1408696062869659649

Spanish doctors have been treating 421 Covid patients with antihistamines (dexchlorpheniramine, cetirizine or loratadine=claritin) and azithromycin and conclude: “The treatment is curative.”

https://www.sciencedirect.com/science/article/pii/S1094553921000018

Executive summary – mortality:

Treatment Home (Yepes): 6/90 (6.67%)

Other Home (Pooled Data – Albacete): 303/1084 (28.0%)

The doctors in the 2 treatment homes only figured out what to do after a few patients died.  So even that mortality is a bit higher than it would have been had this been some sort of structured trial, rather than some clever doctors reacting in real time during a pandemic.

And it turns out, antihistamines were also useful for close contact prophylaxis.

And they also mention those pesky mast cells too:

Although this study is descriptive, our results bear some similarities with other studies [26,36,37]. Mast cells seem to play an important role in the inflammatory responses by releasing granules of histamine, in addition to synthesizing and secrete inflammatory lipid mediators and pro-inflammatory cytokines TNF-α and IL-6 [38]. The use of antihistamines may help to minimize the histamine-mediated cytokine storm [39].

Given the low fatality rate observed in our patient population, this treatment protocol merits immediate consideration for the treatment of COVID-19 and future evaluation in randomized controlled clinical trials, taking into account the probably decisive role of antihistamines, which was the only treatment most of our patients received.

Something to think about if you can’t get ivermectin.  Or – perhaps – even if you can.

  • Sat, Jun 26, 2021 - 08:32am

    #2
    Canuck21

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    Antihistamines Again: Spanish Nursing Home Study

An excellently written and interesting study. I wonder how much effect the nasal hygiene had

“Nasal washing and gargling with sodium bicarbonate water (half a glass of warm water with half a teaspoon of sodium bicarbonate).”

What a cruel joke it would be on humanity if only antihistamines + azithromycin could have stopped many of these deaths and made the beta-version of the “vaccines” unnecessary. But I guess that joke has already happened due to ivermectin.

  • Sat, Jun 26, 2021 - 08:38am

    #3
    LBL

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    Antihistamines Again: Spanish Nursing Home Study

>>>  Nasal washing and gargling with sodium bicarbonate water

 

Alkaline (pH above 7.0) = good for your teeth (as long as it’s not too alkaline.)

Partially Neutralizes the acids that eat at your teeth while you’re sleeping … and while you’re awake.

  • Sat, Jun 26, 2021 - 09:12am

    #4
    davefairtex

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    publication date

Note that the study period ended in June 30 2020.  It took from then, until April 2021 to see this study published.

“No rush, Science Direct.”

One more tidbit:

The mean age of our population was 85 and 48% were over 80 years. No hospital admissions, deaths, nor adverse drug effects were reported in our patient population. By the end of June, 100% of the residents had positive serology for COVID-19.

All those 80-year-olds – all of them – tested positive.

Kinda looks from where I sit – antihistamines beat ivermectin.

Both, together, would seem unbeatable.

“Its too bad” the study took so long to get published.

And based on the FLCCC experience, I’m guessing that delay wasn’t due to the doctors.

  • Sat, Jun 26, 2021 - 09:44am

    #5
    davefairtex

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    can’t resist

I can’t resist.

Loretadine = Claritin.  It is $25.

And Dexchlorpheniramine, same family as diphenhydramine = Benadryl.  It is $10.

Just translating from chemicalese-to-brand-name.

  • Sat, Jun 26, 2021 - 09:57am

    #6
    Mysterymet

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    Reply To: Antihistamines Again: Spanish Nursing Home Study

Any word on Allegra? That is the one I take for my seasonal allergies. I supposed I could switch to Claritin but I like allegra better for the actual allergies…

so zyrtec is cetirizine…

 

  • Sat, Jun 26, 2021 - 10:18am   (Reply to #6)

    #7
    Curt504

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    Antihistamines Again: Spanish Nursing Home Study

Mystery, others prob will comment, that its Mast cell mediation that is the mechanism so any antihistamine is at this point in understandings are likely equivalents.

I agree, crazy what is now coming out about alternative virual infection adjunavents.   The value of this and other discoveries has wider value then covid-19.  Amazing times.

  • Sat, Jun 26, 2021 - 10:29am

    #8
    davefairtex

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    allergy season

So, uh, I have to ask: when does “allergy season” start?

Might explain “seasonality” of COVID19.  Depending on how many people take anti-allergy meds at the start of “allergy season.”

Which turns out to be COVID19 prophylaxis.

Seriously my mind is blown here.

 

  • Sat, Jun 26, 2021 - 10:40am

    #9
    westcoastjan

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    Antihistamines Again: Spanish Nursing Home Study

Way to go, Dave. You keep coming up with amazing, actionable info. This really helps to reduce the fear factor. I know I feel more in control when there are simple things I can do to help myself be well and stay well.

Thanks for all your efforts to get quality info to us – it is beyond appreciated!

Keep up the great work! 👍

  • Sat, Jun 26, 2021 - 10:40am

    #10
    Blaggers

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    Antihistamines Again: Spanish Nursing Home Study

Holy Moly Dave.

Good find. That’s amazing.

We use Aerius. I’ll be checking the active ingredients.

I’d suggest going out and stocking up ASAP.

 

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