2016 study about creating bat viruses infectious to humans. Please read.

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  • Mon, Apr 13, 2020 - 02:23pm

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    Johnw199

    Johnw199

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    2016 study about creating bat viruses infectious to humans. Please read.

Engineering Coronaviruses to Evaluate Emergence and Pathogenic Potential.

https://www.sciencedirect.com/science/article/pii/S0966842X16300038

In order to predict whether a SARS-related bat CoV, named WIV1-CoV, discovered in Chinese horseshoe bats in Yunnan [6], had the potential to emerge in humans, Menachery et al. synthesized a full-DNA clone based on the sequence of the virus [1]. The clone was shown to be able to generate infectious virus in primary human airway epithelial cell culture, confirming its ability to efficiently replicate in human cells. When the spike gene of WIV1-CoV was used to replace that of SARS-CoV MA15, a mouse-adapted virus [7], the resulting CoV did not replicate efficiently or cause disease in mice. However, if transgenic mice that expressed the ACE2 receptor were used, WIV1-CoV was able to replicate and cause weight loss. These experiments showed that WIV1-CoV actually has significant potential to emerge in humans.

Recently, there has been much discussion and debate on the potential threats of gain-of-function experiments [10]. There are fears that accidental release of these ‘super-virulent’ viruses or their use as biological weapons may lead to uncontrollable epidemics. However, we believe that these gain-of-function experiments should not be banned because of the potential threats. By contrast, each experiment should be carefully examined for the potential benefits weighed against potential threats. In our opinion,

  • Mon, Apr 13, 2020 - 05:51pm

    #2
    Janie-em

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    Very interesting, thank you.

“However, we believe…”

Uh huh, the hubris and arrogance is palpable. Curse them and all the other “gain of function” mad scientists who have unleashed this whirlwind on us. They are fooling themselves if they think they can contain these Frankenviruses. Never mind the Nuclear Age, we are in the Age of the Bioweapon and things are just getting started.

Also interesting is their last line :

“In our opinion, the potential benefits are enormous,”

Of course they are, to researchers greedy for gold and glory and Gates Foundation Grants.

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