• Daily Digest

    Daily Digest 4/20 – Coronavirus Leading To Dangerous Medication Shortages, Who Really Decides When America Reopens?

    by Daily Digest

    Monday, April 20, 2020, 7:57 AM


Economy

The coronavirus is leading to dangerous shortages of key medications (Roger B.)

In December, before cases of COVID-19, the illness caused by the coronavirus, were reported in China, the Democratic staff on Peters’s committee compiled a report on “cost, supply and security threats” to the nation’s inventory of prescription drugs. The report concluded “active drug shortages in the United States” were “at their highest levels in almost five years” due to multiple factors including diminished U.S. manufacturing capacity and “overdependence on foreign pharmaceutical supply chains.” Those existing issues have all been exacerbated by the coronavirus crisis.

The coronavirus’ impact on Social Security is now plainly visible (Sparky1)

Single-filing taxpayers with modified adjusted gross income (MAGI) plus one-half of benefits above $25,000 will owe some amount of federal tax on a portion of their Social Security payout. For couples filing jointly, this MAGI-plus-one-half-of-benefits formula begins taxation above $32,000.

More than half of Los Angeles workers are now unemployed just one month into coronavirus lockdowns (Adam)

The Labor Department announced on Thursday that another 5.2 million Americans filed jobless claims, bringing the total number of claims to over 22 million just over the past four weeks.

Labs testing for Covid-19 dispute Dr. Birx’s claim (Sparky1)

CNN’s Drew Griffin reports on a claim that Dr. Deborah Birx made during the White House task-force press briefing that all health care workers in the US could have been tested for coronavirus if machines were running at capacity.

Who Really Decides When America Reopens? (Epictetus)

Our society is based on a system of voluntary compliance. It’s robust glue for a properly functioning society. But, if you think the virus spreads fast – wait until you see the exponential growth in non-compliance when people start to suffer in mass… like when tens of millions lose their jobs.

Let’s talk about reopening the economy (John B.)

Video

Americans at World Health Organization transmitted real-time information about coronavirus to Trump administration (Sparky1)

The presence of so many U.S. officials undercuts President Trump’s assertion that the WHO’s failure to communicate the extent of the threat, born of a desire to protect China, is largely responsible for the rapid spread of the virus in the United States.

The administration has also sharply criticized the Chinese government for withholding information.

Contamination at CDC lab likely cause of testing delay (Sparky1)

Contamination in manufacturing the Centers for Disease Control and Prevention test for the coronavirus caused weeks of delays that slowed the US response to the pandemic, multiple health officials have told CNN. CNN’s Sara Murray has more.

Oil suffers record plunge below $11 amid historic glut (Sparky1)

Crude stockpiles at Cushing — America’s key storage hub — have jumped 48% to almost 55 million barrels since the end of February. The hub had working storage capacity of 76 million as of Sept. 30, according to the Energy Information Administration.

South Korea’s New Coronavirus Twist: Recovered Patients Test Positive Again (Stella)

Many had volunteered for re-examination after exhibiting symptoms such as coughing. Others submitted to extra testing on little more than a hunch despite not showing symptoms. So far, these patients—all of whom needed to twice test negative before leaving medical supervision—haven’t spread the virus to others, local health officials say.

Emergency room doctor, near death with coronavirus, saved after experimental treatment (Doris A.)

Soon after being admitted to his own hospital with a fever, cough and difficulty breathing, he was placed on a ventilator. Five days after that, his lungs and kidneys were failing, his heart was in trouble, and doctors figured he had a day or so to live.

He owes his survival to an elite team of doctors who tried an experimental treatment pioneered in China and used on the sickest of all COVID-19 patients.

Now Comes The Real Crazy (thc0655)

Then came the pandemic that not only ratified QE but expanded it to cover pretty much any financial asset anywhere, while sending government deficits to levels last seen during World War II. The IMF now projects that by year-end global debt will be $8 trillion higher than it would have been otherwise. Advanced economy sovereign debt will surge from 105% of GDP to 122% — in one year.

The looming derivative crisis (thc0655)

But wait, there is another table that breaks derivative exposure down even further into categories, and it turns out the earlier figures are consolidated totals. The true total of OTC derivatives and exchange traded derivatives to which the bank is exposed is €37.121 trillion. That is nearly thirty-five thousand times the €1.062bn netted difference in the balance sheet. And when you bear in mind that valuing OTC derivatives is somewhat subjective, or as the cynics say, mark to myth, it invalidates the valuation exercise.

Chinese Coronavirus Is a Man Made Virus According to Luc Montagnier the Man Who Discovered HIV (Dutch Boomer)

“With my colleague, bio-mathematician Jean-Claude Perez, we carefully analyzed the description of the genome of this RNA virus,” explains Luc Montagnier, interviewed by Dr Jean-François Lemoine for the daily podcast at Pourquoi Docteur, adding that others have already explored this avenue: Indian researchers have already tried to publish the results of the analyses that showed that this coronavirus genome contained sequences of another virus, … the HIV virus (AIDS virus), but they were forced to withdraw their findings as the pressure from the mainstream was too great.

Coronavirus: 38 days when Britain sleepwalked into disaster (UnusualKnowledge)

The virus had spread from China to six countries and was almost certainly in many others. Sensing the coming danger, the British government briefly went into wartime mode that day, holding a meeting of Cobra, its national crisis committee.

How Many Avocado Toasts Does it Take to Buy a Millennial a House? (Brigid L.)

Millennials may enjoy purchasing mimosas and catios more than previous generations, but it’s clear that they aren’t entirely to blame for delaying life’s milestones. We wanted to see just exactly how many avocado toasts you’d really need to cut to buy a house to prove that millennials’ fun financial choices aren’t actually driving their financial woes.

Oil Prices Hit $15 For The First Time In 21 Years (Michael S.)

As the COVID-19 crisis continues to weigh on global oil demand, the price of crude has hit levels not seen in 21 years.

Oil falls on concern over storage and earnings (Sparky1)

The mood in other markets was also cautious as the first-quarter earnings season gets underway. Analysts expect STOXX 600 companies to post a 22% plunge in earnings, which would represent the steepest decline since the 2008 global financial meltdown, IBES data from Refinitiv showed.

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6 Comments

  • Mon, Apr 20, 2020 - 9:13am

    #1

    AKGrannyWGrit

    Status: Silver Member

    Joined: Feb 06 2011

    Posts: 1057

    2

    A Letter To The Future

    Worth listening to.

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  • Mon, Apr 20, 2020 - 10:27am

    #2

    thc0655

    Status: Platinum Member

    Joined: Apr 27 2010

    Posts: 2134

    3

    City shelter operators told they can safely disregard wearing masks

    Anecdote from Philadelphia:

    The City has sent a notice to homeless shelter providers that they can safely ignore the Governor's order for people to wear masks when in groups. "To put your minds at ease, Governor Wolf's order that takes effect tonight regarding masks will not affect your operations." This is Orwellian doublespeak at its best. If there's a group of people that we should be prioritizing to wear masks it's the residents and heroic staff of the city's shelter system, who serve almost 5,000 high risk individuals every minute of every day without the protections that they desperately need. Masks are hard to find, of course. But, that doesn't mean the City doesn't have any. They just have higher priorities for them than the most at risk.

    🤦‍♂️

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  • Mon, Apr 20, 2020 - 1:37pm

    #3

    Mark_BC

    Status: Bronze Member

    Joined: Apr 30 2010

    Posts: 437

    1

    Mark_BC said:

    WTI now minus $23?

    https://oilprice.com/oil-price-charts

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  • Mon, Apr 20, 2020 - 2:07pm

    #4

    thc0655

    Status: Platinum Member

    Joined: Apr 27 2010

    Posts: 2134

    7

    What I worry about

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  • Mon, Apr 20, 2020 - 8:27pm

    #5

    sand_puppy

    Status: Platinum Member

    Joined: Apr 13 2011

    Posts: 2476

    6

    What is behind the "hydroxychloroquine has no evidence" line?

    I don't know who is behind it.

    I can guess that there could be pharmaceutical companies that stand to make 100s of billions on alternative treatments (Roche's Actemra (tocilizumab) and Gilead Science's Remdesivir, to start with).

    Or it could be more of a power play where some faction hopes to create chaos, then  "restore order" with powerful social controls.  But first, sufficient trauma and chaos is required.

    In the earliest days of the pandemic and before even the first testing stations were set up, the governors of 11 states issued emergency orders to prohibit outpatient pharmacies from filling prescriptions for hydroxychloroquine for the purpose of treating or preventing COVID.  New York lead, then Rhode Island, New Hampshire and others.  The promptness and decisiveness of this act, in what otherwise looked a circus of ineffective floundering, smacks of coordination and preplanning.

    But one thing is very clear.  There are 1) basic science articles showing that chloroquine/hydroqychloroquine have understandable basic cellular mechanisms of action, 2) that there is a narrow time window in the disease process--at the very beginning-- when benefit is possible, and 3) that there are the multiple clinical reports of experienced doctors who have seen benefit.

    I will review.

    Remdesivir and Chloroquine Effectively Inhibit The Recently Emerged Novel CoronaVirus in Vitro.    Cell Research volume 30, pages269–271(2020)  From February 2020, China.

    ---

    From Antimicrob Agents Chemother. 2014 Aug;58(8):4875-84.  Scientist screening already approved drugs finding 4 that were effective in inhibiting several coronaviruses. These included chloroquine, chlorpromazine, loperamide, and lopinavir.  Only chloroquine and lopinavir inhibited CoV at the blood levels reached by normal dosing.  These would be obvious starting places.

    -------

    An older article from Lancet 2004 explained that chloroquine has antiviral properties and explains 2 of the 3 main mechanisms of action. (The 3rd mechanism, the zinc ionophore effect, was discovered later).

    Chloroquine, known since 1934,  exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses.  Endocytosis of viral particles is inhibited by the alkaline chloroquine.

    ...chloroquine has immunomodulatory effects, suppressing the production and release of tumour necrosis factor α and interleukin 6, which mediate the inflammatory complications of several viral diseases.  (Larger pictures in original article.)

    ..this old drug may experience a revival in the clinical management of viral diseases such as AIDS and SARS [a coronavirus infection].

    -----

    And, Zinc has been demonstrated to be an inhibitor of the enzyme that the coronaviruses use to copy their genetic material.  This has a profound effect on the survival of coronavirus infections in laboratory cell cultures.  This enzyme is called "RNA dependent RNA polymerase," (RdRp).

    Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

    Author's Summary:  Positive-stranded RNA (+RNA) viruses include many important pathogens [including influenza and coronaviruses]. ... RNA-dependent RNA polymerase (RdRp) functions as the core enzyme of their RNA-synthesizing machinery. ...  Given their crucial function in the viral replicative cycle, RdRps are key targets for antiviral research. Increased intracellular Zn2+ concentrations are known to efficiently impair replication of a number of RNA viruses, e.g. by interfering with correct proteolytic processing of viral polyproteins. Here, we ... show that coronavirus replication can be inhibited by increased Zn2+ levels ...

    In cell culture, [the zinc ionophore] PT stimulates Zn2+ uptake within minutes and inhibits RNA virus replication.

    There are zinc ionophores that could fill a similar ionophore role in living people.  It looks like there are several in clinical use.

    1)  Chloroquine Is a Zinc Ionophore  (and hydroxychloroquine)

    2)  Quercitin and EGOG are Zinc Ionophores and play multiple roles in intracellular signaling, anti-oxidant activity--probably through the mechanism of increasing intracellular zinc.

    And there are numerous clinical studies where HCQ/Chlor has been used with reported benefit.

    French researcher Didier Raoult has now treated 1,000 coronavirus patient with 99.3% success rate.   Methods here, results here

    And Vladimir (Zev) Zelinko is a Family Practice doctor to a poor very close-knit community just outside NYC with rampant COVID infections.  He started Zn/HCQ/Azithromycin at the first sign of illness.  He reports less than 5 of his 338 patient needed to be hospitalized.

    When COVID runs loose in a nursing home the infection rates and mortality is typically very high.  In Texas, Dr. Robin Armstrong is the medical director of The Resort at Texas City nursing home.  When 89 residents and workers tested positive for COVID he treated early with 5 days of HCQ/Azith.  None needed hospitalization nor died.  Clinically they recovered with the resolution of fevers and no shortness of breath.  This is very remarkable.

    Summary:   That the press and the traditional medical authorities consistently continue to assert that "there is no evidence"when faced with clear evidence (of moderate strength), low cost and a good safety profile, and a pressing need for immediate treatment, I must assume that there is a coordinated--but hidden--social re-engineering attempt going on.

     

     

     

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  • Mon, Apr 20, 2020 - 8:38pm

    Truth9834

    Truth9834

    Status: Member

    Joined: Feb 05 2020

    Posts: 30

    1

    I agree - scroll down and take a look at the interview with Doctor Buckmaster.

    https://www.tristatehomepage.com/news/coronavirus-watch/tri-state-doctor-treating-covid-19-patients-with-hydroxychloroquine/

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